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Recombinant Human High mobility group protein B1 (HMGB1), partial

Recombinant Human High mobility group protein B1 (HMGB1), partial — (Microbial infection) Facilitates dengue virus propagation via interaction with the untranslated regions of viral genome. Purity >90%.

SKU: BCRECP-000839 Category:
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Product Specifications

Product SkuBCRECP-000839
Product DescriptionRecombinant Human High mobility group protein B1 (HMGB1) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 8-179aa. [Accession | P09429].
Uniprot No.P09429
Gene NamesHMGB1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region8-179aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight47.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

(Microbial infection) Facilitates dengue virus propagation via interaction with the untranslated regions of viral genome. In turn, this interaction with viral RNA may regulate secondary structure of dengue RNA thus facilitating its recognition by the replication complex.

Biological Context

Subcellular Location: Endoplasmic reticulum
Tissue Specificity: Ubiquitous. Expressed in platelets

Product Specifications

Recombinant Human High mobility group protein B1 (HMGB1), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 8-179aa, with N-terminal GST-tagged tag, molecular weight 47.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Facilitates dengue virus propagation via interaction with the untranslated regions of viral genome. In turn, this interaction with viral RNA may regulate secondary structure of dengue RNA thus facilitating its recognition by the replication complex

Subcellular Location

Endoplasmic reticulum

Tissue Specificity

Ubiquitous. Expressed in platelets (PubMed:11154118)

Subunit

(Microbial infection) Interacts with influenza A virus protein NP; this interaction promotes viral replication

Gene: HMGB1  |  Organism: Homo sapiens  |  Synonyms: High mobility group protein 1
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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