Recombinant Human Interleukin-1 receptor-like 1 (IL1RL1), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 35.8 kDa, purity >95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
,

Recombinant Human Interleukin-1 receptor-like 1 (IL1RL1), partial (Active)

Recombinant Human Interleukin-1 receptor-like 1 (IL1RL1), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-000515 Categories: ,
Online Inquiry →
Product SKUBCACP-000515
Product DescriptionRecombinant Human Interleukin-1 receptor-like 1 (IL1RL1) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 19-323aa. [Accession | Q01638].
Uniprot No.Q01638
Gene NamesIL1RL1
PurityGreater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region19-323aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight35.8 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Human ROR2 at 2 μg/mL can bind Anti-ROR2 recombinant antibody .The EC50 is 0.8067-0.9971 ng/mL.;ROR2 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Human ROR2 with an affinity constant of 0.17 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesInterleukin-1 receptor-like 1; EC:3.2.2.6; Protein ST2; IL1RL1; DER4, ST2, T1

Function

Inhibits IL-33 signaling.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein)
Tissue Specificity: Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle. Expressed on T-cells in fibrotic liver; at protein level. Overexpressed in fibrotic and cirrhotic liver

Product Specifications

Recombinant Human Interleukin-1 receptor-like 1 (IL1RL1), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 19-323aa, with C-terminal 10xHis-tagged tag, molecular weight 35.8 kDa, purity Greater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Human ROR2 at 2 μg/mL can bind Anti-ROR2 recombinant antibody .The EC50 is 0.8067-0.9971 ng/mL.;ROR2 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Human ROR2 with an affinity constant of 0.17 nM as detected by MetaSPR Assay (WeSPRTM 200).

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Inhibits IL-33 signaling

Subcellular Location

Cell membrane (Single-pass type I membrane protein)

Tissue Specificity

Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle. Expressed on T-cells in fibrotic liver; at protein level. Overexpressed in fibrotic and cirrhotic liver

Subunit

Interacts with MYD88, IRAK1, IRAK4, and TRAF6. Bound to its ligand IL-33, interacts with IL1RAP to form the minimal interleukin-33 signaling complex with a 1:1:1 stoichiometry. Interacts with KIT (bound to KITLG/SCF). A mast cell-specific KITLG/SCF-induced interleukin-33 signaling complex contains IL1RL1, IL1RAP, KIT and MYD88. Interacts with TMED1 (PubMed:23319592)

Gene: IL1RL1  |  Organism: Homo sapiens  |  Synonyms: Protein ST2
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top