Function
Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system.
Product Specifications
Recombinant Human Interleukin-1 receptor-like 2 (IL1RL2), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 20-335aa, with C-terminal 10xHis-tagged tag, molecular weight 37.3 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications. Explore more Interleukin proteins →
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Human IGF2 at 2 μg/mL can bind anti-IGF2 recombinant antibody.The EC50 is 13.00-14.55 ng/mL.;IGF2 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Human IGF2 with an affinity constant of 0.213 nM as detected by MetaSPR Assay (WeSPRTM 200).
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
