Recombinant Human Interleukin-12 receptor subunit beta-1(IL12RB1),partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 58.5 kDa, purity >95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
,

Recombinant Human Interleukin-12 receptor subunit beta-1(IL12RB1),partial (Active)

Recombinant Human Interleukin-12 receptor subunit beta-1(IL12RB1),partial (Active) — Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Purity >95%.

SKU: BCACP-000296 Categories: ,
Online Inquiry →
Product SKUBCACP-000296
Product DescriptionRecombinant Human Interleukin-12 receptor subunit beta-1(IL12RB1) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 24-540aa. [Accession | P42701].
Uniprot No.P42701
Gene NamesIL12RB1
PurityGreater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region24-540aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight58.5 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis IL1RAP at 2 μg/mL can bind Anti-IL1RAP recombinant antibody . The EC50 is 0.9099-1.181 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesIL12R, IL12RB

Function

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Also associates with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Product Specifications

Recombinant Human Interleukin-12 receptor subunit beta-1(IL12RB1),partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 24-540aa, with C-terminal 10xHis-tagged tag, molecular weight 58.5 kDa, purity Greater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis IL1RAP at 2 μg/mL can bind Anti-IL1RAP recombinant antibody . The EC50 is 0.9099-1.181 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Also associates with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade

Gene: IL12RB1  |  Organism: Homo sapiens

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top