Recombinant Human Interleukin-21 (IL21), partial (Active) (GMP), Homo sapiens (Human), E.Coli, Tag-Free, 15.4 kDa, purity >> 98 % by SDS-PAGE and HPLC analyses.
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Recombinant Human Interleukin-21 (IL21), partial (Active) (GMP)

Recombinant Human Interleukin-21 (IL21), partial (Active) (GMP) — Cytokine with immunoregulatory activity. Purity > 98 % by SDS-PAGE and HPLC analyses..

SKU: BCACP-001063 Categories: ,
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Product SKUBCACP-001063
Product DescriptionRecombinant Human Interleukin-21 (IL21), (GMP) protein is expressed from E.Coli with Tag-Free. It contains 23-155aa. [Accession | Q9HBE4].
Uniprot No.Q9HBE4
Gene NamesIL21
Purity> 98 % by SDS-PAGE and HPLC analyses.
Expression SystemE.Coli
Expression Region23-155aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight15.4 kDa
ActivityThe ED50 as determined by its ability to activate chimeric receptor and induce reporter gene expression in HEK293 cell line used Splite TEV activity detection platform is less than 10 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesCVID11; IL 21; IL-21; Il21; IL21_HUMAN; Interleukin 21; Interleukin-21; interleukin-21 isoform; Interleukin21; OTTHUMP00000164088; Za11

Function

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells.

Product Specifications

Recombinant Human Interleukin-21 (IL21), partial (Active) (GMP) is a recombinant protein, expressed in E.Coli, covering amino acids 23-155aa, with Tag-Free tag, molecular weight 15.4 kDa, purity > 98 % by SDS-PAGE and HPLC analyses.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: The ED50 as determined by its ability to activate chimeric receptor and induce reporter gene expression in HEK293 cell line used Splite TEV activity detection platform is less than 10 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (PubMed:11081504, PubMed:15178704). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity)

Gene: IL21  |  Organism: Homo sapiens

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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