Recombinant Human Interleukin-21 receptor (IL21R), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 26.7 kDa, purity >95% as determined by SDS-PAGE.
,

Recombinant Human Interleukin-21 receptor (IL21R), partial (Active)

Recombinant Human Interleukin-21 receptor (IL21R), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-000603 Categories: ,
Online Inquiry →
Product SKUBCACP-000603
Product DescriptionRecombinant Human Interleukin-21 receptor (IL21R) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 20-236aa. [Accession | Q9HBE5].
Uniprot No.Q9HBE5
Gene NamesIL21R
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region20-236aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight26.7 kDa
ActivityMeasured by its ability to cleave the fluorogenic peptide substrate, MCA-Arg-Pro-Lys-Pro-Val-Glu-NVAL-Trp-Arg-Lys(DNP)NH2. The specific activity is >50 pmol/min/µg.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesInterleukin-21 receptor; IL-21 receptor; IL-21R; Novel interleukin receptor; CD antigen CD360

Function

This is a receptor for interleukin-21.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)
Tissue Specificity: Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen
Disease Association: Immunodeficiency 56 (IMD56) : An autosomal recessive primary immunodeficiency characterized by B- and T-cell defects and variable dysfunction of NK cells. Patients tend to have normal numbers of lymphocytes, but show defective class-switched B-cells, low IgG, defective antibody response, and defective T-cell responses to certain antigens. [The disease is caused by variants affecting the gene represented in this entry] | [Chromosomal aberrations involving IL21R is a cause of B-cell non-Hodgkin lymphomas (B-cell NHL). Translocation t(3;16)(q27;p11), with BCL6]

Product Specifications

Recombinant Human Interleukin-21 receptor (IL21R), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 20-236aa, with C-terminal 10xHis-tagged tag, molecular weight 26.7 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

This is a receptor for interleukin-21

Subcellular Location

Membrane (Single-pass type I membrane protein)

Disease Association

Immunodeficiency 56 (IMD56) : An autosomal recessive primary immunodeficiency characterized by B- and T-cell defects and variable dysfunction of NK cells. Patients tend to have normal numbers of lymphocytes, but show defective class-switched B-cells, low IgG, defective antibody response, and defective T-cell responses to certain antigens. [The disease is caused by variants affecting the gene represented in this entry] | [Chromosomal aberrations involving IL21R is a cause of B-cell non-Hodgkin lymphomas (B-cell NHL). Translocation t(3;16)(q27;p11), with BCL6]

Tissue Specificity

Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen

Subunit

Heterodimer with the common gamma subunit. Associates with JAK1

Gene: IL21R  |  Organism: Homo sapiens  |  Synonyms: Novel interleukin receptor
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

Shopping Cart
Scroll to Top