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Recombinant Macaca fascicularis Interleukin-21 receptor (IL21R), partial (Active)

Recombinant Macaca fascicularis Interleukin-21 receptor (IL21R), partial (Active) — recombinant protein from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-000632 Categories: ,
Product SKUBCACP-000632
Product DescriptionRecombinant Cynomolgus monkey Interleukin-21 receptor (IL21R) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 41-253aa. [Accession | G7Q0S8].
Uniprot No.G7Q0S8
Gene NamesIL21R
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region41-253aa
SpeciesMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Tag InfoC-terminal 10xHis-tagged
Molecular weight26.2 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis IL21R at 2 μg/mL can bind Human IL21. The EC50 is 15.01-19.43 ng/mL.;Measured by its binding ability in a functional ELISA. Immobilized Human IL21R at 2 μg/mL can bind Human IL21. The EC50 is 16.65-19.49 ng/mL.;Human IL21 captured on Protein A Chip can bind Recombinant Macaca fascicularis IL21R with an affinity constant of 1.31 nM as detected by MetaSPR Assay (WeSPRTM 200).;Human IL21 captured on Protein A Chip can bind Recombinant Human IL21R with an affinity constant of 1.87 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesInterleukin-21 receptor; Novel interleukin receptor

Function

This is a receptor for interleukin-21.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)

Product Specifications

Recombinant Macaca fascicularis Interleukin-21 receptor (IL21R), partial (Active) is a recombinant protein from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), expressed in Mammalian cell, covering amino acids 41-253aa, with C-terminal 10xHis-tagged tag, molecular weight 26.2 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis IL21R at 2 μg/mL can bind Human IL21. The EC50 is 15.01-19.43 ng/mL.;Measured by its binding ability in a functional ELISA. Immobilized Human IL21R at 2 μg/mL can bind Human IL21. The EC50 is 16.65-19.49 ng/mL.;Human IL21 captured on Protein A Chip can bind Recombinant Macaca fascicularis IL21R with an affinity constant of 1.31 nM as detected by MetaSPR Assay (WeSPRTM 200).;Human IL21 captured on Protein A Chip can bind Recombinant Human IL21R with an affinity constant of 1.87 nM as detected by MetaSPR Assay (WeSPRTM 200).

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

This is a receptor for interleukin-21

Subcellular Location

Membrane (Single-pass type I membrane protein)

Subunit

Heterodimer with the common gamma subunit. Associates with JAK1

Organism: Macaca fascicularis  |  Synonyms: Novel interleukin receptor

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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