Recombinant Human Interleukin-23 receptor (IL23R), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal hFc-tagged, 65 kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Interleukin-23 receptor (IL23R), partial (Active)

Recombinant Human Interleukin-23 receptor (IL23R), partial (Active) — Associates with IL12RB1 to form the interleukin-23 receptor. Purity >90%.

SKU: BCACP-001010 Categories: ,
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Product SKUBCACP-001010
Product DescriptionRecombinant Human Interleukin-23 receptor (IL23R) protein is expressed from Mammalian cell with C-terminal hFc-tagged. It contains 24-353aa. [Accession | Q5VWK5].
Uniprot No.Q5VWK5
Gene NamesIL23R
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region24-353aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc-tagged
Molecular weight65 kDa
ActivityThe ED50 as determined in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells is 40-200pg/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesIL 23R; IL-23 receptor; IL-23R; IL23 Receptor; Il23r; IL23R_HUMAN; Interleukin 23 receptor ; Interleukin-23 receptor

Function

Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues.

Product Specifications

Recombinant Human Interleukin-23 receptor (IL23R), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 24-353aa, with C-terminal hFc-tagged tag, molecular weight 65 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: The ED50 as determined in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells is 40-200pg/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis

Gene: IL23R  |  Organism: Homo sapiens

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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