Recombinant Human Leucine-rich repeat-containing protein 15 (LRRC15), partial, Homo sapiens (Human), Mammalian cell, C-terminal hFc1-tagged, 86.7kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Leucine-rich repeat-containing protein 15 (LRRC15), partial

Recombinant Human Leucine-rich repeat-containing protein 15 (LRRC15), partial — (Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein. Purity >95%.

SKU: BCRECP-001086 Category:
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Product Specifications

Product SkuBCRECP-001086
Product DescriptionRecombinant Human Leucine-rich repeat-containing protein 15 (LRRC15) Protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 22-538aa. [Accession | Q8TF66].
Uniprot No.Q8TF66
Gene NamesLRRC15
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region22-538aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight86.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

(Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein. Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein)
Tissue Specificity: Expressed in brain and placenta. Expressed in lung fibroblasts. Expressed in chodrocytes

Product Specifications

Recombinant Human Leucine-rich repeat-containing protein 15 (LRRC15), partial is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 22-538aa, with C-terminal hFc1-tagged tag, molecular weight 86.7kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein (PubMed:36228039, PubMed:36735681, PubMed:36757924). Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells (PubMed:36228039, PubMed:36757924)

Subcellular Location

Cell membrane (Single-pass type I membrane protein)

Tissue Specificity

Expressed in brain and placenta (PubMed:11785964). Expressed in lung fibroblasts (PubMed:36228039, PubMed:36757924). Expressed in chodrocytes (PubMed:34702854)

Subunit

(Microbial infection) Interacts with human coronavirus SARS-CoV-2 spike protein (via RBD domain); the interaction is direct

Gene: LRRC15  |  Organism: Homo sapiens  |  Synonyms: Leucine-rich repeat protein induced by beta-amyloid homolog
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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