Recombinant Human Leucine-rich repeat LGI family member 4 (LGI4), Homo sapiens (Human), E.coli, N-terminal 6xHis-tagged, 61.6kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Leucine-rich repeat LGI family member 4 (LGI4)

Recombinant Human Leucine-rich repeat LGI family member 4 (LGI4) — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.

SKU: BCRECP-001063 Category:
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Product Specifications

Product SkuBCRECP-001063
Product DescriptionRecombinant Human Leucine-rich repeat LGI family member 4 (LGI4) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 20-537aa. [Accession | Q8N135].
Uniprot No.Q8N135
Gene NamesLGI4
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region20-537aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight61.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

Component of Schwann cell signaling pathway(s) that controls axon segregation and myelin formation.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Widely expressed, with highest expression in brain
Disease Association: Arthrogryposis multiplex congenita 1, neurogenic, with myelin defect (AMC1) : A form of arthrogryposis multiplex congenita, a developmental condition characterized by multiple joint contractures resulting from reduced or absent fetal movements. AMC1 is an autosomal recessive severe form with onset in utero. Most affected individuals die in utero. Those who survive have generalized contractures and hypotonia. The disorder is caused by a neurogenic defect and poor or absent myelin formation around peripheral nerves rather than by a muscular defect. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Leucine-rich repeat LGI family member 4 (LGI4) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 20-537aa, with N-terminal 6xHis-tagged tag, molecular weight 61.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Component of Schwann cell signaling pathway(s) that controls axon segregation and myelin formation (By similarity)

Subcellular Location

Secreted

Disease Association

Arthrogryposis multiplex congenita 1, neurogenic, with myelin defect (AMC1) : A form of arthrogryposis multiplex congenita, a developmental condition characterized by multiple joint contractures resulting from reduced or absent fetal movements. AMC1 is an autosomal recessive severe form with onset in utero. Most affected individuals die in utero. Those who survive have generalized contractures and hypotonia. The disorder is caused by a neurogenic defect and poor or absent myelin formation around peripheral nerves rather than by a muscular defect. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Widely expressed, with highest expression in brain

Subunit

Can bind to ADAM11, ADAM22 and ADAM23

Gene: LGI4  |  Organism: Homo sapiens  |  Synonyms: LGI1-like protein 3; Leucine-rich glioma-inactivated protein 4
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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