Function
Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Biological Context
Subcellular Location: Secreted
Tissue Specificity: Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine
Product Specifications
Recombinant Human Lymphotactin protein (XCL1), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 23-114aa, with Tag-Free tag, molecular weight 10.2 kDa, purity >98% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
