Recombinant Mouse Lymphotactin protein (Xcl1) (Active)

Recombinant Mouse Lymphotactin protein (Xcl1) (Active) — Chemotactic activity for lymphocytes but not for monocytes or neutrophils. Purity >97%.

SKU: BCACP-000837 Category:
Product SKUBCACP-000837
Product DescriptionRecombinant Mouse Lymphotactin protein (Xcl1) protein is expressed from E.Coli with Tag-Free. It contains 22-114aa. [Accession | P47993].
Uniprot No.P47993
Gene NamesXcl1
Purity>97% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region22-114aa
SpeciesMus musculus (Mouse)
Tag InfoTag-Free
Molecular weight10.1 kDa
ActivityFully biologically active when compared to standard. The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50 ng/ml, corresponding to a specific activity of >2.0x104 IU/mg.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesXcl1; Lptn; Ltn; Scyc1; Lymphotactin; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; Small-inducible cytokine C1

Function

Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed in activated CD8(+) T cells. In the thymus, expressed by medullary thymic epithelial cells

Product Specifications

Recombinant Mouse Lymphotactin protein (Xcl1) (Active) is a recombinant protein from Mus musculus (Mouse), expressed in E.Coli, covering amino acids 22-114aa, with Tag-Free tag, molecular weight 10.1 kDa, purity >97% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment

Subcellular Location

Secreted

Tissue Specificity

Expressed in activated CD8(+) T cells. In the thymus, expressed by medullary thymic epithelial cells

Gene: Xcl1  |  Organism: Mus musculus  |  Synonyms: C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; Small-inducible cytokine C1

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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