Recombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1), partial (Active)

Recombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-001264 Category:
Product SKUBCACP-001264
Product DescriptionRecombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1) protein is expressed from Mammalian cell with C-terminal hFc-tagged. It contains 29-382aa. [Accession | P11279].
Uniprot No.P11279
Gene NamesLAMP1
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region29-382aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc-tagged
Molecular weight65.5 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human 4-1BB-Fc-His at 2μg/ml can bind Anti-Human CD137 mAb, the ED50 of Anti-Human CD137 mAb is 0.41ug/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesLAMP1; Lysosome-associated membrane glycoprotein 1; LAMP-1; Lysosome-associated membrane protein 1; CD107 antigen-like family member A; CD antigen CD107a

Function

(Microbial infection) Supports the FURIN-mediated cleavage of mumps virus fusion protein F by interacting with both FURIN and the unprocessed form but not the processed form of the viral protein F.

Biological Context

Subcellular Location: Lysosome membrane (Single-pass type I membrane protein); Endosome membrane (Single-pass type I membrane protein); Late endosome membrane (Single-pass type I membrane protein); Cell membrane (Single-pass type I membrane protein); Cytolytic granule membrane (Single-pass type I membrane protein)

Product Specifications

Recombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 29-382aa, with C-terminal hFc-tagged tag, molecular weight 65.5 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human 4-1BB-Fc-His at 2μg/ml can bind Anti-Human CD137 mAb, the ED50 of Anti-Human CD137 mAb is 0.41ug/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

(Microbial infection) Supports the FURIN-mediated cleavage of mumps virus fusion protein F by interacting with both FURIN and the unprocessed form but not the processed form of the viral protein F

Subcellular Location

Lysosome membrane (Single-pass type I membrane protein); Endosome membrane (Single-pass type I membrane protein); Late endosome membrane (Single-pass type I membrane protein); Cell membrane (Single-pass type I membrane protein); Cytolytic granule membrane (Single-pass type I membrane protein)

Subunit

(Microbial infection) Interacts with mumps virus protein F; this interaction promotes protein F cleavage by FURIN

Gene: LAMP1  |  Organism: Homo sapiens  |  Synonyms: CD107 antigen-like family member A
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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