Recombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal hFc-tagged, 65.5 kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1), partial (Active)

Recombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-001264 Category:
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Product SKUBCACP-001264
Product DescriptionRecombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1) protein is expressed from Mammalian cell with C-terminal hFc-tagged. It contains 29-382aa. [Accession | P11279].
Uniprot No.P11279
Gene NamesLAMP1
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region29-382aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc-tagged
Molecular weight65.5 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human 4-1BB-Fc-His at 2μg/ml can bind Anti-Human CD137 mAb, the ED50 of Anti-Human CD137 mAb is 0.41ug/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesLAMP1; Lysosome-associated membrane glycoprotein 1; LAMP-1; Lysosome-associated membrane protein 1; CD107 antigen-like family member A; CD antigen CD107a

Function

(Microbial infection) Supports the FURIN-mediated cleavage of mumps virus fusion protein F by interacting with both FURIN and the unprocessed form but not the processed form of the viral protein F.

Biological Context

Subcellular Location: Lysosome membrane (Single-pass type I membrane protein); Endosome membrane (Single-pass type I membrane protein); Late endosome membrane (Single-pass type I membrane protein); Cell membrane (Single-pass type I membrane protein); Cytolytic granule membrane (Single-pass type I membrane protein)

Product Specifications

Recombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 29-382aa, with C-terminal hFc-tagged tag, molecular weight 65.5 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

(Microbial infection) Supports the FURIN-mediated cleavage of mumps virus fusion protein F by interacting with both FURIN and the unprocessed form but not the processed form of the viral protein F

Subcellular Location

Lysosome membrane (Single-pass type I membrane protein); Endosome membrane (Single-pass type I membrane protein); Late endosome membrane (Single-pass type I membrane protein); Cell membrane (Single-pass type I membrane protein); Cytolytic granule membrane (Single-pass type I membrane protein)

Subunit

(Microbial infection) Interacts with mumps virus protein F; this interaction promotes protein F cleavage by FURIN

Gene: LAMP1  |  Organism: Homo sapiens  |  Synonyms: CD107 antigen-like family member A
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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