Recombinant Human Mannan-binding lectin serine protease 2 (MASP2), Homo sapiens (Human), Baculovirus, C-terminal 6xHis-tagged, 79.8kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Human Mannan-binding lectin serine protease 2 (MASP2)

Recombinant Human Mannan-binding lectin serine protease 2 (MASP2) — recombinant protein from Homo sapiens (Human), expressed in Baculovirus. Purity >85%.

SKU: BCRECP-001130 Categories: , ,
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Product Specifications

Product SkuBCRECP-001130
Product DescriptionRecombinant Human Mannan-binding lectin serine protease 2 (MASP2) Protein is expressed from Baculovirus with C-terminal 6xHis-tagged. It contains 16-686aa. [Accession | O00187].
Uniprot No.O00187
Gene NamesMASP2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemBaculovirus
Expression Region16-686aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight79.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

Serine protease component of the lectin complement pathway, which catalyzes cleavage and activation of C2 and C4, the next components of the complement pathway.

Biological Context

Subcellular Location: Secreted; Cell surface
Tissue Specificity: Plasma
Disease Association: MASP2 deficiency (MASPD) : A disorder that results in autoimmune manifestations, recurrent severe infections, and chronic inflammatory disease. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Mannan-binding lectin serine protease 2 (MASP2) is a recombinant protein from Homo sapiens (Human), expressed in Baculovirus, covering amino acids 16-686aa, with C-terminal 6xHis-tagged tag, molecular weight 79.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Serine protease component of the lectin complement pathway, which catalyzes cleavage and activation of C2 and C4, the next components of the complement pathway

Subcellular Location

Secreted; Cell surface

Disease Association

MASP2 deficiency (MASPD) : A disorder that results in autoimmune manifestations, recurrent severe infections, and chronic inflammatory disease. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Plasma

Subunit

Homodimer; disulfide-linked (PubMed:15117939, PubMed:15364579). Interacts with MBL2 and FCN2; requires calcium ions (PubMed:15117939). Interacts with SERPING1 (PubMed:10946292). Interacts with guianensin, an anticoagulant and anti-complement protein from Simulium guianense saliva; the interaction results in the inhibition of MASP2 enzymatic activity (PubMed:39924859)

Gene: MASP2  |  Organism: Homo sapiens  |  Synonyms: MBL-associated serine protease 2; Mannose-binding protein-associated serine protease 2
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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