Recombinant Human Mannan-binding lectin serine protease 2 (MASP2), Homo sapiens (Human), Baculovirus, C-terminal 6xHis-tagged, 79.8kDa, purity >85% as determined by SDS-PAGE.
, ,

Recombinant Human Mannan-binding lectin serine protease 2 (MASP2)

Recombinant Human Mannan-binding lectin serine protease 2 (MASP2) — recombinant protein from Homo sapiens (Human), expressed in Baculovirus. Purity >85%.

SKU: BCRECP-001130 Categories: , ,
Online Inquiry →

Product Specifications

Product SkuBCRECP-001130
Product DescriptionRecombinant Human Mannan-binding lectin serine protease 2 (MASP2) Protein is expressed from Baculovirus with C-terminal 6xHis-tagged. It contains 16-686aa. [Accession | O00187].
Uniprot No.O00187
Gene NamesMASP2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemBaculovirus
Expression Region16-686aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight79.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

Serine protease component of the lectin complement pathway, which catalyzes cleavage and activation of C2 and C4, the next components of the complement pathway.

Biological Context

Subcellular Location: Secreted; Cell surface
Tissue Specificity: Plasma
Disease Association: MASP2 deficiency (MASPD) : A disorder that results in autoimmune manifestations, recurrent severe infections, and chronic inflammatory disease. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Mannan-binding lectin serine protease 2 (MASP2) is a recombinant protein from Homo sapiens (Human), expressed in Baculovirus, covering amino acids 16-686aa, with C-terminal 6xHis-tagged tag, molecular weight 79.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Serine protease component of the lectin complement pathway, which catalyzes cleavage and activation of C2 and C4, the next components of the complement pathway

Subcellular Location

Secreted; Cell surface

Disease Association

MASP2 deficiency (MASPD) : A disorder that results in autoimmune manifestations, recurrent severe infections, and chronic inflammatory disease. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Plasma

Subunit

Homodimer; disulfide-linked (PubMed:15117939, PubMed:15364579). Interacts with MBL2 and FCN2; requires calcium ions (PubMed:15117939). Interacts with SERPING1 (PubMed:10946292). Interacts with guianensin, an anticoagulant and anti-complement protein from Simulium guianense saliva; the interaction results in the inhibition of MASP2 enzymatic activity (PubMed:39924859)

Gene: MASP2  |  Organism: Homo sapiens  |  Synonyms: MBL-associated serine protease 2; Mannose-binding protein-associated serine protease 2
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

Shopping Cart
Scroll to Top