Recombinant Human Membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3), partial

Recombinant Human Membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3), partial — Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Purity >90%.

SKU: BCRECP-001387 Category:

Product Specifications

Product SkuBCRECP-001387
Product DescriptionRecombinant Human Membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 387-597aa. [Accession | Q9BZ71].
Uniprot No.Q9BZ71
Gene NamesPITPNM3
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region387-597aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight30.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions.

Biological Context

Subcellular Location: Endomembrane system (Peripheral membrane protein)
Tissue Specificity: Detected in brain and spleen, and at low levels in ovary
Disease Association: Cone-rod dystrophy 5 (CORD5) : An inherited retinal dystrophy characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa, due to cone photoreceptors degenerating at a higher rate than rod photoreceptors. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 387-597aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 30.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity). Binds calcium ions

Subcellular Location

Endomembrane system (Peripheral membrane protein)

Disease Association

Cone-rod dystrophy 5 (CORD5) : An inherited retinal dystrophy characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa, due to cone photoreceptors degenerating at a higher rate than rod photoreceptors. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Detected in brain and spleen, and at low levels in ovary

Subunit

Interacts with PTK2B via its C-terminus

Gene: PITPNM3  |  Organism: Homo sapiens  |  Synonyms: Phosphatidylinositol transfer protein, membrane-associated 3; Pyk2 N-terminal domain-interacting receptor 1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

Shopping Cart
Scroll to Top