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Recombinant Human metapneumovirus Fusion glycoprotein F0 (F) Protein

Recombinant Human metapneumovirus Fusion glycoprotein F0 (F) Protein — Major determinant of the species specificity of RSV infection. Purity >85%.

SKU: BCRECP-00435TM Categories: ,

Product Specifications

Uniprot No.Q6WB98
Gene NamesF
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region19-539aa
SpeciesHuman metapneumovirus (strain CAN97-83) (HMPV)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight72.4kDa
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Major determinant of the species specificity of RSV infection. The trimer of F1-F2 (F protein) also facilitates the attachment to host cell by binding to host heparan sulfate.

Biological Context

Subcellular Location: Virion membrane (Single-pass type I membrane protein); Host cell membrane (Single-pass membrane protein)

Product Specifications

Recombinant Human metapneumovirus Fusion glycoprotein F0 (F) Protein is a recombinant protein from Human metapneumovirus (strain CAN97-83) (HMPV), expressed in in vitro E.coli expression system, covering amino acids 19-539aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 72.4kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Major determinant of the species specificity of RSV infection (By similarity). The trimer of F1-F2 (F protein) also facilitates the attachment to host cell by binding to host heparan sulfate (PubMed:22238303)

Subcellular Location

Virion membrane (Single-pass type I membrane protein); Host cell membrane (Single-pass membrane protein)

Subunit

Homotrimer. Heterodimer with fusion protein F1; disulfide-linked. As a heterodimer with F1, interacts with host heparan sulfate (PubMed:22238303). As a heterodimer with F2, interacts with host integrin ITGAV/ITGB1 (PubMed:19164533). Part of a complex composed of F1, F2 and G glycoproteins (By similarity)

Gene: F  |  Organism: Human metapneumovirus (strain CAN97-83)

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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