Recombinant Human Neurotrophic factor BDNF precursor form (BDNF), Homo sapiens (Human), E.coli, N-terminal 6xHis-Myc-tagged, 31.0kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Human Neurotrophic factor BDNF precursor form (BDNF)

Recombinant Human Neurotrophic factor BDNF precursor form (BDNF) — Important signaling molecule that activates signaling cascades downstream of NTRK2. Purity >85%.

SKU: BCRECP-000158 Categories: ,
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Product Specifications

Product SkuBCRECP-000158
Product DescriptionRecombinant Human Neurotrophic factor BDNF precursor form (BDNF) Protein is expressed from E.coli with N-terminal 6xHis-Myc-tagged. It contains 19-247aa. [Accession | P23560].
Uniprot No.P23560
Gene NamesBDNF
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region19-247aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-Myc-tagged
Molecular weight31.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD).

Product Specifications

Recombinant Human Neurotrophic factor BDNF precursor form (BDNF) is a recombinant protein, expressed in E.coli, covering amino acids 19-247aa, with N-terminal 6xHis-Myc-tagged tag, molecular weight 31.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2 (PubMed:24908487, PubMed:29909994). Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse (By similarity)

Gene: BDNF  |  Organism: Homo sapiens

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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