Recombinant Human Prolow-density lipoprotein receptor-related protein 1 (LRP1), partial, Homo sapiens (Human), E.coli, C-terminal 6xHis-tagged, 53.0kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Prolow-density lipoprotein receptor-related protein 1 (LRP1), partial

Recombinant Human Prolow-density lipoprotein receptor-related protein 1 (LRP1), partial — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >95%.

SKU: BCRECP-001082 Category:
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Product Specifications

Product SkuBCRECP-001082
Product DescriptionRecombinant Human Prolow-density lipoprotein receptor-related protein 1 (LRP1) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 2522-2941aa. [Accession | Q07954].
Uniprot No.Q07954
Gene NamesLRP1
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region2522-2941aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight53.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

(Microbial infection) Functions as a receptor for yellow fever virus.

Biological Context

Subcellular Location: Golgi outpost; Cytoplasm, cytoskeleton, microtubule organizing center
Tissue Specificity: Most abundant in liver, brain and lung
Disease Association: Keratosis pilaris atrophicans (KPA) : A group of rare genodermatoses characterized by keratotic follicular papules, variable degrees of inflammation, and secondary atrophic scarring. Most cases are associated with an atopic diathesis and keratosis pilaris on the extensor extremities. KPA is comprised of three distinct clinical subtypes: keratosis pilaris atrophicans faciei, atrophoderma vermiculatum, and keratosis follicularis spinulosa decalvans. Affected individuals may present with features overlapping the 3 subtypes. [The disease is caused by variants affecting the gene represented in this entry] | Developmental dysplasia of the hip 3 (DDH3) : An autosomal dominant form of congenital dysplasia of the hip, a common skeletal anomaly in which the normal seating of the femoral head in the acetabulum is disrupted. Its severity ranges from mild instability of the femoral head with slight capsular laxity, permitting minimal lateral displacement, through moderate lateral displacement of the femoral head, without loss of contact of the head with the acetabulum, up to complete dislocation of the femoral head from the acetabulum. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Prolow-density lipoprotein receptor-related protein 1 (LRP1), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 2522-2941aa, with C-terminal 6xHis-tagged tag, molecular weight 53.0kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

(Microbial infection) Functions as a receptor for yellow fever virus

Subcellular Location

Golgi outpost; Cytoplasm, cytoskeleton, microtubule organizing center

Disease Association

Keratosis pilaris atrophicans (KPA) : A group of rare genodermatoses characterized by keratotic follicular papules, variable degrees of inflammation, and secondary atrophic scarring. Most cases are associated with an atopic diathesis and keratosis pilaris on the extensor extremities. KPA is comprised of three distinct clinical subtypes: keratosis pilaris atrophicans faciei, atrophoderma vermiculatum, and keratosis follicularis spinulosa decalvans. Affected individuals may present with features overlapping the 3 subtypes. [The disease is caused by variants affecting the gene represented in this entry] | Developmental dysplasia of the hip 3 (DDH3) : An autosomal dominant form of congenital dysplasia of the hip, a common skeletal anomaly in which the normal seating of the femoral head in the acetabulum is disrupted. Its severity ranges from mild instability of the femoral head with slight capsular laxity, permitting minimal lateral displacement, through moderate lateral displacement of the femoral head, without loss of contact of the head with the acetabulum, up to complete dislocation of the femoral head from the acetabulum. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Most abundant in liver, brain and lung

Subunit

(Microbial infection) Interacts with yellow fever virus envelope protein E; this interaction facilitates virus entry

Gene: LRP1  |  Organism: Homo sapiens  |  Synonyms: Alpha-2-macroglobulin receptor; Apolipoprotein E receptor
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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