Recombinant Human Ras-related protein Rab-33A (RAB33A), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 28.0kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Ras-related protein Rab-33A (RAB33A)

Recombinant Human Ras-related protein Rab-33A (RAB33A) — The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Purity >85%.

SKU: BCRECP-001504 Category:
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Product Specifications

Product SkuBCRECP-001504
Product DescriptionRecombinant Human Ras-related protein Rab-33A (RAB33A) Protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 1-237aa. [Accession | Q14088].
Uniprot No.Q14088
Gene NamesRAB33A
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region1-237aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight28.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Modulates autophagosome formation through interaction with ATG16L1.

Biological Context

Subcellular Location: Cell membrane (Lipid-anchor)
Tissue Specificity: Expressed only in lymphoid cell lines

Product Specifications

Recombinant Human Ras-related protein Rab-33A (RAB33A) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 1-237aa, with C-terminal 10xHis-tagged tag, molecular weight 28.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Modulates autophagosome formation through interaction with ATG16L1 (By similarity)

Subcellular Location

Cell membrane (Lipid-anchor)

Tissue Specificity

Expressed only in lymphoid cell lines

Subunit

Interacts with ATG16L1; the interaction is important for autophagosome formation

Gene: RAB33A  |  Organism: Homo sapiens  |  Synonyms: Small GTP-binding protein S10

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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