Recombinant Human Syndecan-1 (SDC1), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 39.9kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Syndecan-1 (SDC1), partial

Recombinant Human Syndecan-1 (SDC1), partial — Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Purity >90%.

SKU: BCRECP-001592 Category:
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Product Specifications

Product SkuBCRECP-001592
Product DescriptionRecombinant Human Syndecan-1 (SDC1) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 23-254aa. [Accession | P18827].
Uniprot No.P18827
Gene NamesSDC1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region23-254aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight39.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein); Secreted; Secreted, extracellular exosome
Tissue Specificity: Detected in placenta (at protein level). Detected in fibroblasts (at protein level)

Product Specifications

Recombinant Human Syndecan-1 (SDC1), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 23-254aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 39.9kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity). Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity)

Subcellular Location

Membrane (Single-pass type I membrane protein); Secreted; Secreted, extracellular exosome

Tissue Specificity

Detected in placenta (at protein level) (PubMed:32337544). Detected in fibroblasts (at protein level) (PubMed:36213313)

Subunit

Interacts with CDCP1. Interacts (via C-terminus) with TIAM1 (via PDZ domain). Interacts with MDK (By similarity)

Gene: SDC1  |  Organism: Homo sapiens
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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