Recombinant Human Syndecan-1 (SDC1), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 25.2 kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Syndecan-1 (SDC1), partial (Active)

Recombinant Human Syndecan-1 (SDC1), partial (Active) — Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Purity >95%.

SKU: BCACP-000602 Category:
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Product SKUBCACP-000602
Product DescriptionRecombinant Human Syndecan-1 (SDC1) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 23-254aa. [Accession | P18827].
Uniprot No.P18827
Gene NamesSDC1
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region23-254aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight25.2 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Macaca mulatta APLNR at 4 μg/mL can bind Anti-APLNR recombinant antibody . The EC50 is 20.44-25.30 ng/mL. The VLPs is negative control.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesSyndecan-1; SYND1; CD antigen CD138

Function

Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein); Secreted; Secreted, extracellular exosome
Tissue Specificity: Detected in placenta (at protein level). Detected in fibroblasts (at protein level)

Product Specifications

Recombinant Human Syndecan-1 (SDC1), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 23-254aa, with C-terminal 10xHis-tagged tag, molecular weight 25.2 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity). Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity)

Subcellular Location

Membrane (Single-pass type I membrane protein); Secreted; Secreted, extracellular exosome

Tissue Specificity

Detected in placenta (at protein level) (PubMed:32337544). Detected in fibroblasts (at protein level) (PubMed:36213313)

Subunit

Interacts with CDCP1. Interacts (via C-terminus) with TIAM1 (via PDZ domain). Interacts with MDK (By similarity)

Gene: SDC1  |  Organism: Homo sapiens
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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