Recombinant Human Syndecan-1 (SDC1), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 25.2 kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Syndecan-1 (SDC1), partial (Active)

Recombinant Human Syndecan-1 (SDC1), partial (Active) — Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Purity >95%.

SKU: BCACP-000602 Category:
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Product SKUBCACP-000602
Product DescriptionRecombinant Human Syndecan-1 (SDC1) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 23-254aa. [Accession | P18827].
Uniprot No.P18827
Gene NamesSDC1
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region23-254aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight25.2 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Macaca mulatta APLNR at 4 μg/mL can bind Anti-APLNR recombinant antibody . The EC50 is 20.44-25.30 ng/mL. The VLPs is negative control.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesSyndecan-1; SYND1; CD antigen CD138

Function

Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein); Secreted; Secreted, extracellular exosome
Tissue Specificity: Detected in placenta (at protein level). Detected in fibroblasts (at protein level)

Product Specifications

Recombinant Human Syndecan-1 (SDC1), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 23-254aa, with C-terminal 10xHis-tagged tag, molecular weight 25.2 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca mulatta APLNR at 4 μg/mL can bind Anti-APLNR recombinant antibody . The EC50 is 20.44-25.30 ng/mL. The VLPs is negative control.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity). Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity)

Subcellular Location

Membrane (Single-pass type I membrane protein); Secreted; Secreted, extracellular exosome

Tissue Specificity

Detected in placenta (at protein level) (PubMed:32337544). Detected in fibroblasts (at protein level) (PubMed:36213313)

Subunit

Interacts with CDCP1. Interacts (via C-terminus) with TIAM1 (via PDZ domain). Interacts with MDK (By similarity)

Gene: SDC1  |  Organism: Homo sapiens
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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