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Recombinant Human T-lymphocyte activation antigen CD80 (CD80), partial (Active)

Recombinant Human T-lymphocyte activation antigen CD80 (CD80), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-000651 Categories: ,
Product SKUBCACP-000651
Product DescriptionRecombinant Human T-lymphocyte activation antigen CD80 (CD80) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 35-242aa. [Accession | P33681].
Uniprot No.P33681
Gene NamesCD80
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region35-242aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight25.2 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Mouse Vegfa at 2 μg/mL can bind Mouse Kdr. The EC50 is 12.64-13.88 ng/mL.;Recombinant Mouse Kdr captured on Protein A Chip can bind Recombinant Mouse Vegfa with an affinity constant of 3.24 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesT-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80

Function

(Microbial infection) Acts as a receptor for adenovirus subgroup B.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein)
Tissue Specificity: Expressed on the surfaces of antigen-presenting cells

Product Specifications

Recombinant Human T-lymphocyte activation antigen CD80 (CD80), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 35-242aa, with C-terminal 10xHis-tagged tag, molecular weight 25.2 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Mouse Vegfa at 2 μg/mL can bind Mouse Kdr. The EC50 is 12.64-13.88 ng/mL.;Recombinant Mouse Kdr captured on Protein A Chip can bind Recombinant Mouse Vegfa with an affinity constant of 3.24 nM as detected by MetaSPR Assay (WeSPRTM 200).

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

(Microbial infection) Acts as a receptor for adenovirus subgroup B

Subcellular Location

Cell membrane (Single-pass type I membrane protein)

Tissue Specificity

Expressed on the surfaces of antigen-presenting cells

Subunit

(Microbial infection) Interacts with Orthopoxvirus OPG038/M2 protein, inhibiting the interaction with CTLA4/CD152

Gene: CD80  |  Organism: Homo sapiens  |  Synonyms: Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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