Recombinant Human Thymosin beta-4 (TMSB4X) (Active)

Recombinant Human Thymosin beta-4 (TMSB4X) (Active) — Potent inhibitor of bone marrow derived stem cell differentiation. Purity >97%.

SKU: BCACP-000867 Category:
Product SKUBCACP-000867
Product DescriptionRecombinant Human Thymosin beta-4 (TMSB4X) protein is expressed from E.Coli with Tag-Free. It contains 2-44aa. [Accession | P62328].
Uniprot No.P62328
Gene NamesTMSB4X
Purity>97% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region2-44aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight4.9 kDa
ActivityFully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 μg/ml, corresponding to a specific activity of >200 IU/mg.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesFx; Hematopoietic system regulatory peptide; Prothymosin beta 4; PTMB 4; PTMB4; Seraspenide; T beta 4; T beta-4; TB4X; THYB 4; Thyb4; Thymosin beta 4; Thymosin beta 4 X chromosome; Thymosin beta 4 X linked; TMSB 4; TMSB4; Tmsb4x; TYB4_HUMAN

Function

Potent inhibitor of bone marrow derived stem cell differentiation. Acts by inhibits the entry of hematopoietic pluripotent stem cells into the S-phase.

Biological Context

Subcellular Location: Cytoplasm, cytoskeleton
Tissue Specificity: Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells

Product Specifications

Recombinant Human Thymosin beta-4 (TMSB4X) (Active) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 2-44aa, with Tag-Free tag, molecular weight 4.9 kDa, purity >97% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 μg/ml, corresponding to a specific activity of >200 IU/mg.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Potent inhibitor of bone marrow derived stem cell differentiation (PubMed:7694679). Acts by inhibits the entry of hematopoietic pluripotent stem cells into the S-phase (By similarity)

Subcellular Location

Cytoplasm, cytoskeleton

Tissue Specificity

Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells

Subunit

Identified in a complex composed of ACTA1, COBL, GSN AND TMSB4X (PubMed:23009842). Interacts with SERPINB1 (By similarity)

Gene: TMSB4X  |  Organism: Homo sapiens  |  Synonyms: Fx
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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