Recombinant Human Transient receptor potential cation channel subfamily V member 2 (TRPV2)-Detergent Protein, Homo sapiens (Human), Mammalian cell, N-terminal 10xHis-tagged and C-terminal Twin-Strep-tagged, 90.5kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Transient receptor potential cation channel subfamily V member 2 (TRPV2)-Detergent Protein

Recombinant Human Transient receptor potential cation channel subfamily V member 2 (TRPV2)-Detergent Protein — Calcium-permeable, non-selective cation channel. Purity >85%.

SKU: BCRECP-00521TM Category:
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Product Specifications

Uniprot No.Q9Y5S1
Gene NamesTRPV2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region1-764aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged and C-terminal Twin-Strep-tagged
Molecular weight90.5kDa
ActivityNot Test
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Calcium-permeable, non-selective cation channel. Seems to be regulated, at least in part, by growth factors, such as IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein); Cytoplasm; Melanosome

Product Specifications

Recombinant Human Transient receptor potential cation channel subfamily V member 2 (TRPV2)-Detergent Protein is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 1-764aa, with N-terminal 10xHis-tagged and C-terminal Twin-Strep-tagged tag, molecular weight 90.5kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not Test

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Calcium-permeable, non-selective cation channel (PubMed:10201375). Seems to be regulated, at least in part, by growth factors, such as IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells (By similarity)

Subcellular Location

Cell membrane (Multi-pass membrane protein); Cytoplasm; Melanosome

Subunit

Homotetramer (By similarity). Interacts with a cAMP-dependent protein kinase type II regulatory subunit (PRKAR2A or PRKAR2B) and ACBD3 (By similarity). Interacts with SLC50A1; the interaction probably occurs intracellularly and depends on TRPV2 N-glycosylation (By similarity)

Gene: TRPV2  |  Organism: Homo sapiens  |  Synonyms: Osm-9-like TRP channel 2; Vanilloid receptor-like protein 1
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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