Recombinant Rat Transient receptor potential cation channel subfamily V member 2 (Trpv2) Protein, Rattus norvegicus (Rat), in vitro E.coli expression system, N-terminal 10xHis-tagged, 88.2kDa, purity >85% as determined by SDS-PAGE.

Recombinant Rat Transient receptor potential cation channel subfamily V member 2 (Trpv2) Protein

Recombinant Rat Transient receptor potential cation channel subfamily V member 2 (Trpv2) Protein — Calcium-permeable, non-selective cation channel. Purity >85%.

SKU: BCRECP-00181TM Category:
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Product Specifications

Uniprot No.Q9WUD2
Gene NamesTrpv2
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region1-761aa
SpeciesRattus norvegicus (Rat)
Tag InfoN-terminal 10xHis-tagged
Molecular weight88.2kDa
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Calcium-permeable, non-selective cation channel. Seems to be regulated, at least in part, by growth factors, such as IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein); Cytoplasm; Melanosome
Tissue Specificity: Ubiquitously expressed. Expressed in dorsal root ganglia, trigeminal ganglia, spinal cord (Lissauer's tract, dorsal horn and dorsal columns) (at protein level)

Product Specifications

Recombinant Rat Transient receptor potential cation channel subfamily V member 2 (Trpv2) Protein is a recombinant protein from Rattus norvegicus (Rat), expressed in in vitro E.coli expression system, covering amino acids 1-761aa, with N-terminal 10xHis-tagged tag, molecular weight 88.2kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Calcium-permeable, non-selective cation channel (PubMed:10201375, PubMed:15249591, PubMed:39972168). Seems to be regulated, at least in part, by growth factors, such as IGF1, PDGF and morphogenetic neuropeptide/head activator (By similarity). May transduce physical stimuli in mast cells (PubMed:15249591)

Subcellular Location

Cell membrane (Multi-pass membrane protein); Cytoplasm; Melanosome

Tissue Specificity

Ubiquitously expressed. Expressed in dorsal root ganglia, trigeminal ganglia, spinal cord (Lissauer's tract, dorsal horn and dorsal columns) (at protein level)

Subunit

Homotetramer (PubMed:39972168). Interacts with a cAMP-dependent protein kinase type II regulatory subunit (PRKAR2A or PRKAR2B) and ACBD3 (PubMed:15249591). Interacts with SLC50A1; the interaction probably occurs intracellularly and depends on TRPV2 N-glycosylation (PubMed:14991772)

Gene: Trpv2  |  Organism: Rattus norvegicus  |  Synonyms: Osm-9-like TRP channel 2; Stretch-activated channel 2B; Vanilloid receptor-like protein 1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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