Recombinant Human Tropomodulin-1 (TMOD1), Homo sapiens (Human), E.coli, N-terminal GST-tagged, 67.6kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Tropomodulin-1 (TMOD1)

Recombinant Human Tropomodulin-1 (TMOD1) — Blocks the elongation and depolymerization of the actin filaments at the pointed end. Purity >90%.

SKU: BCRECP-001785 Category:
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Product Specifications

Product SkuBCRECP-001785
Product DescriptionRecombinant Human Tropomodulin-1 (TMOD1) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 1-359aa. [Accession | P28289].
Uniprot No.P28289
Gene NamesTMOD1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-359aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight67.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.

Biological Context

Subcellular Location: Cytoplasm, cytoskeleton
Tissue Specificity: Highly expressed in the erythrocyte, heart and skeletal muscle

Product Specifications

Recombinant Human Tropomodulin-1 (TMOD1) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-359aa, with N-terminal GST-tagged tag, molecular weight 67.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Blocks the elongation and depolymerization of the actin filaments at the pointed end (PubMed:38168645). The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus

Subcellular Location

Cytoplasm, cytoskeleton

Tissue Specificity

Highly expressed in the erythrocyte, heart and skeletal muscle

Subunit

Binds to the N-terminus of tropomyosin and to actin. Interacts with FLII

Gene: TMOD1  |  Organism: Homo sapiens  |  Synonyms: Erythrocyte tropomodulin
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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