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Recombinant Human Tumor-associated calcium signal transducer 2 (TACSTD2), partial, Biotinylated (Active)

Recombinant Human Tumor-associated calcium signal transducer 2 (TACSTD2), partial, Biotinylated (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-000625 Categories: , ,
Product SKUBCACP-000625
Product DescriptionRecombinant Human Tumor-associated calcium signal transducer 2 (TACSTD2), Biotinylated protein is expressed from Mammalian cell with C-terminal 10xHis-Avi-tagged. It contains 31-274aa. [Accession | P09758].
Uniprot No.P09758
Gene NamesTACSTD2
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region31-274aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-Avi-tagged
Molecular weight31.1 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human CD6 at 2 μg/mL can bind Human ALCAM . The EC50 is 1.049-1.226 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesTumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1

Function

May function as a growth factor receptor.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)
Tissue Specificity: Placenta, pancreatic carcinoma cell lines
Disease Association: Corneal dystrophy, gelatinous drop-like (GDLD) : A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Tumor-associated calcium signal transducer 2 (TACSTD2), partial, Biotinylated (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 31-274aa, with C-terminal 10xHis-Avi-tagged tag, molecular weight 31.1 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD6 at 2 μg/mL can bind Human ALCAM . The EC50 is 1.049-1.226 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

May function as a growth factor receptor

Subcellular Location

Membrane (Single-pass type I membrane protein)

Disease Association

Corneal dystrophy, gelatinous drop-like (GDLD) : A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Placenta, pancreatic carcinoma cell lines

Gene: TACSTD2  |  Organism: Homo sapiens  |  Synonyms: Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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