Recombinant Human Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial, Homo sapiens (Human), Mammalian cell, N-terminal hFc-tagged, 42.8kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Human Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial

Recombinant Human Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial — Cytokine that binds to TNFRSF4. Purity >85%.

SKU: BCRECP-001814 Categories: ,
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Product Specifications

Product SkuBCRECP-001814
Product DescriptionRecombinant Human Tumor necrosis factor ligand superfamily member 4 (TNFSF4) Protein is expressed from Mammalian cell with N-terminal hFc-tagged. It contains 51-183aa. [Accession | P23510].
Uniprot No.P23510
Gene NamesTNFSF4
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region51-183aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal hFc-tagged
Molecular weight42.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.

Biological Context

Subcellular Location: Membrane (Single-pass type II membrane protein)
Disease Association: Systemic lupus erythematosus (SLE) : A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. [Disease susceptibility is associated with variants affecting the gene represented in this entry. The upstream region of TNFSF4 contains a single risk haplotype for SLE, which is correlated with increased expression of both cell-surface TNFSF4 and TNFSF4 transcripts. Increased levels of TNFSF4 are thought to augment T-cell-APC interaction and the functional consequences of T-cell activation, thereby destabilizing peripheral tolerance]

Product Specifications

Recombinant Human Tumor necrosis factor ligand superfamily member 4 (TNFSF4), partial is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 51-183aa, with N-terminal hFc-tagged tag, molecular weight 42.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production

Subcellular Location

Membrane (Single-pass type II membrane protein)

Disease Association

Systemic lupus erythematosus (SLE) : A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. [Disease susceptibility is associated with variants affecting the gene represented in this entry. The upstream region of TNFSF4 contains a single risk haplotype for SLE, which is correlated with increased expression of both cell-surface TNFSF4 and TNFSF4 transcripts. Increased levels of TNFSF4 are thought to augment T-cell-APC interaction and the functional consequences of T-cell activation, thereby destabilizing peripheral tolerance]

Subunit

Homotrimer

Gene: TNFSF4  |  Organism: Homo sapiens  |  Synonyms: Glycoprotein Gp34; OX40 ligand; TAX transcriptionally-activated glycoprotein 1
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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