Recombinant Human Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal hFc1-tagged, 48.5 kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), partial (Active)

Recombinant Human Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >90%.

SKU: BCACP-000035 Categories: ,
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Product SKUBCACP-000035
Product DescriptionRecombinant Human Tumor necrosis factor receptor superfamily member 14 (TNFRSF14) protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 39-202aa. [Accession | Q92956].
Uniprot No.Q92956
Gene NamesTNFRSF14
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region39-202aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight48.5 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized TNFRSF14 at 5 μg/ml can bind human TNFSF14, the EC50 is 49.85-79.31 ng/ml.;Measured by its binding ability in a functional ELISA. Immobilized human TNFRSF14 at 5 μg/ml can bind Biotinylated human TNFSF14 , the EC50 is 1.773-3.707 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesHVEML; ATAR; CD270; CD40 like protein precursor; Herpes virus entry mediator A; Herpesvirus entry mediator A; Herpesvirus entry mediator; Herpesvirus entry mediator ligand; HveA; HVEM; HVEM L; LIGHT; LIGHTR; TNFRSF14; TNFSF 14; TNR14_HUMAN; TR2; Tumor necrosis factor receptor like gene2; Tumor necrosis factor receptor superfamily member 14; Tumor necrosis factor receptor superfamily member 14 precursor; Tumor necrosis factor receptor-like 2

Function

(Microbial infection) Acts as a receptor for Herpes simplex virus 2/HHV-2.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein)
Tissue Specificity: Widely expressed, with the highest expression in lung, spleen and thymus. Expressed in a subpopulation of B cells and monocytes. Expressed in naive T cells

Product Specifications

Recombinant Human Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 39-202aa, with C-terminal hFc1-tagged tag, molecular weight 48.5 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

(Microbial infection) Acts as a receptor for Herpes simplex virus 2/HHV-2

Subcellular Location

Cell membrane (Single-pass type I membrane protein)

Tissue Specificity

Widely expressed, with the highest expression in lung, spleen and thymus. Expressed in a subpopulation of B cells and monocytes (PubMed:18193050). Expressed in naive T cells (PubMed:19915044)

Subunit

(Microbial infection) Interacts with herpes simplex virus 2/HHV-2 envelope glycoprotein D

Gene: TNFRSF14  |  Organism: Homo sapiens  |  Synonyms: Herpes virus entry mediator A; Tumor necrosis factor receptor-like 2
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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