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Recombinant Human Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), partial (Active)

Recombinant Human Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >90%.

SKU: BCACP-000035 Categories: ,
Product SKUBCACP-000035
Product DescriptionRecombinant Human Tumor necrosis factor receptor superfamily member 14 (TNFRSF14) protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 39-202aa. [Accession | Q92956].
Uniprot No.Q92956
Gene NamesTNFRSF14
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region39-202aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight48.5 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized TNFRSF14 at 5 μg/ml can bind human TNFSF14, the EC50 is 49.85-79.31 ng/ml.;Measured by its binding ability in a functional ELISA. Immobilized human TNFRSF14 at 5 μg/ml can bind Biotinylated human TNFSF14 , the EC50 is 1.773-3.707 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesHVEML; ATAR; CD270; CD40 like protein precursor; Herpes virus entry mediator A; Herpesvirus entry mediator A; Herpesvirus entry mediator; Herpesvirus entry mediator ligand; HveA; HVEM; HVEM L; LIGHT; LIGHTR; TNFRSF14; TNFSF 14; TNR14_HUMAN; TR2; Tumor necrosis factor receptor like gene2; Tumor necrosis factor receptor superfamily member 14; Tumor necrosis factor receptor superfamily member 14 precursor; Tumor necrosis factor receptor-like 2

Function

(Microbial infection) Acts as a receptor for Herpes simplex virus 2/HHV-2.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein)
Tissue Specificity: Widely expressed, with the highest expression in lung, spleen and thymus. Expressed in a subpopulation of B cells and monocytes. Expressed in naive T cells

Product Specifications

Recombinant Human Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 39-202aa, with C-terminal hFc1-tagged tag, molecular weight 48.5 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized TNFRSF14 at 5 μg/ml can bind human TNFSF14, the EC50 is 49.85-79.31 ng/ml.;Measured by its binding ability in a functional ELISA. Immobilized human TNFRSF14 at 5 μg/ml can bind Biotinylated human TNFSF14 , the EC50 is 1.773-3.707 ng/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

(Microbial infection) Acts as a receptor for Herpes simplex virus 2/HHV-2

Subcellular Location

Cell membrane (Single-pass type I membrane protein)

Tissue Specificity

Widely expressed, with the highest expression in lung, spleen and thymus. Expressed in a subpopulation of B cells and monocytes (PubMed:18193050). Expressed in naive T cells (PubMed:19915044)

Subunit

(Microbial infection) Interacts with herpes simplex virus 2/HHV-2 envelope glycoprotein D

Gene: TNFRSF14  |  Organism: Homo sapiens  |  Synonyms: Herpes virus entry mediator A; Tumor necrosis factor receptor-like 2
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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