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Recombinant Human Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), partial (Active)

Recombinant Human Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), partial (Active) — Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Purity >95%.

SKU: BCACP-000497 Categories: ,
Product SKUBCACP-000497
Product DescriptionRecombinant Human Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) protein is expressed from Mammalian cell with C-terminal mFc-tagged. It contains 1-54aa. [Accession | Q02223].
Uniprot No.Q02223
Gene NamesTNFRSF17
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region1-54aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal mFc-tagged
Molecular weight35.2 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Human PTH1R(CSB-MP018988HU) at 5 μg/mL can bind Human PTH. The EC50 is 3.156-3.564 μg/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesB-cell maturation protein (CD_antigen: CD269)(BCM) (BCMA)

Function

Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity.

Product Specifications

Recombinant Human Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), partial (Active) — Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Purity >95%. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Human PTH1R(CSB-MP018988HU) at 5 μg/mL can bind Human PTH. The EC50 is 3.156-3.564 μg/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK

Subcellular Location

Cell membrane (Single-pass type III membrane protein); Endomembrane system (Single-pass type III membrane protein)

Disease Association

[A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2]

Tissue Specificity

Expressed in mature B-cells, but not in T-cells or monocytes

Subunit

Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6

Gene: TNFRSF17  |  Organism: Homo sapiens  |  Synonyms: B-cell maturation protein
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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