Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 6xHis-tagged, 21 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (Active)

Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-001279 Categories: ,
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Product SKUBCACP-001279
Product DescriptionRecombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) protein is expressed from Mammalian cell with C-terminal 6xHis-tagged. It contains 29-216aa. [Accession | P43489].
Uniprot No.P43489
Gene NamesTNFRSF4
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region29-216aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight21 kDa
ActivityThe ED50 as determined by its ability to bind Human Galectin-9 in functional ELISA is less than 20 ug/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesTNFRSF4; TXGP1L; Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD antigen CD134

Function

(Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)
Disease Association: Immunodeficiency 16 (IMD16) : An autosomal recessive primary immunodeficiency associated with classic Kaposi sarcoma of childhood and poor T-cell recall immune responses due to complete functional OX40 deficiency. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 29-216aa, with C-terminal 6xHis-tagged tag, molecular weight 21 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

(Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B

Subcellular Location

Membrane (Single-pass type I membrane protein)

Disease Association

Immunodeficiency 16 (IMD16) : An autosomal recessive primary immunodeficiency associated with classic Kaposi sarcoma of childhood and poor T-cell recall immune responses due to complete functional OX40 deficiency. [The disease is caused by variants affecting the gene represented in this entry]

Subunit

(Microbial infection) Interacts with Human herpesvirus 6B/HHV-6B gQ1:gQ2 proteins

Gene: TNFRSF4  |  Organism: Homo sapiens  |  Synonyms: ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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