Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal hFc-tagged, 46.8 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (Active)

Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-001280 Categories: ,
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Product SKUBCACP-001280
Product DescriptionRecombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) protein is expressed from Mammalian cell with C-terminal hFc-tagged. It contains 29-216aa. [Accession | P43489].
Uniprot No.P43489
Gene NamesTNFRSF4
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region29-216aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc-tagged
Molecular weight46.8 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Mouse B7-1-Fc at 5μg/ml can bind Mouse CTLA-4-His, the ED50 of Recombinant Mouse CTLA-4-His is 2-10 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesTNFRSF4; TXGP1L; Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD antigen CD134

Function

(Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)
Disease Association: Immunodeficiency 16 (IMD16) : An autosomal recessive primary immunodeficiency associated with classic Kaposi sarcoma of childhood and poor T-cell recall immune responses due to complete functional OX40 deficiency. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 29-216aa, with C-terminal hFc-tagged tag, molecular weight 46.8 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse B7-1-Fc at 5μg/ml can bind Mouse CTLA-4-His, the ED50 of Recombinant Mouse CTLA-4-His is 2-10 ng/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B

Subcellular Location

Membrane (Single-pass type I membrane protein)

Disease Association

Immunodeficiency 16 (IMD16) : An autosomal recessive primary immunodeficiency associated with classic Kaposi sarcoma of childhood and poor T-cell recall immune responses due to complete functional OX40 deficiency. [The disease is caused by variants affecting the gene represented in this entry]

Subunit

(Microbial infection) Interacts with Human herpesvirus 6B/HHV-6B gQ1:gQ2 proteins

Gene: TNFRSF4  |  Organism: Homo sapiens  |  Synonyms: ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor
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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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