Recombinant Influenza B virus Nuclear export protein (NS), Influenza B virus (strain B/Yamagata/1/1973), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 21.8kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Influenza B virus Nuclear export protein (NS)

Recombinant Influenza B virus Nuclear export protein (NS) — Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs). Purity >85%.

SKU: BCRECP-003911 Categories: , ,
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Product Specifications

Product SkuBCRECP-003911
Product DescriptionRecombinant Influenza B virus Nuclear export protein (NS) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 1-122aa. [Accession | P08014].
Uniprot No.P08014
Gene NamesNS
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-122aa
SpeciesInfluenza B virus (strain B/Yamagata/1/1973)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight21.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasMicrobiology

Function

Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs). Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell. Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.

Biological Context

Subcellular Location: Virion; Host nucleus

Product Specifications

Recombinant Influenza B virus Nuclear export protein (NS) is a recombinant protein from Influenza B virus (strain B/Yamagata/1/1973), expressed in E.coli, covering amino acids 1-122aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 21.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs). Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell. Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain. This domain is believed to allow recognition of RNPs bound to the protein M1. Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized. Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane. May down-regulate viral RNA synthesis when overproduced

Subcellular Location

Virion; Host nucleus

Subunit

Interacts with protein M1. May interact with host nucleoporin RAB/HRB and exportin XPO1/CRM1

Gene: NS  |  Organism: Influenza B virus (strain B/Yamagata/1/1973)  |  Synonyms: Non-structural protein 2

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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