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Recombinant JC polyomavirus Minor capsid protein VP2

Recombinant JC polyomavirus Minor capsid protein VP2 — Viroporin inducing perforation of cellular membranes to trigger virus progeny release. Purity >90%.

SKU: BCRECP-003660 Categories: , ,

Product Specifications

Product SkuBCRECP-003660
Product DescriptionRecombinant JC polyomavirus Minor capsid protein VP2 Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 2-344aa. [Accession | P03095].
Uniprot No.P03095
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region2-344aa
SpeciesJC polyomavirus (JCPyV) (JCV)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight53.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Viroporin inducing perforation of cellular membranes to trigger virus progeny release. Forms pores of 3 nm inner diameter. VP4 is expressed about 24 hours after the late structural proteins and is not incorporated into the mature virion.

Biological Context

Subcellular Location: Host nucleus

Product Specifications

Recombinant JC polyomavirus Minor capsid protein VP2 is a recombinant protein from JC polyomavirus (JCPyV) (JCV), expressed in E.coli, covering amino acids 2-344aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 53.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

Viroporin inducing perforation of cellular membranes to trigger virus progeny release. Forms pores of 3 nm inner diameter. VP4 is expressed about 24 hours after the late structural proteins and is not incorporated into the mature virion (By similarity)

Subcellular Location

Host nucleus

Subunit

Forms homooligomers, and heterooligomers with VP2 in the endoplasmic reticulum membrane. Interacts (via D1 domain) with VP1 (By similarity)

Organism: JC polyomavirus  |  Synonyms: Minor structural protein VP2

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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