Recombinant Macaca fascicularis Angiotensin-converting enzyme (ACE2), partial (Active), Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), Mammalian cell, C-terminal hFc1-tagged, 112.7 kDa, purity >90% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.
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Recombinant Macaca fascicularis Angiotensin-converting enzyme (ACE2), partial (Active)

Recombinant Macaca fascicularis Angiotensin-converting enzyme (ACE2), partial (Active) — recombinant protein from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), expressed in Mammalian cell. Purity >90%.

SKU: BCACP-000084 Categories: ,
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Product SKUBCACP-000084
Product DescriptionRecombinant Cynomolgus monkey Angiotensin-converting enzyme (ACE2) protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 18-741aa. [Accession | A0A2K5X283].
Uniprot No.A0A2K5X283
Gene NamesACE2
PurityGreater than 90% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region18-741aa
SpeciesMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Tag InfoC-terminal hFc1-tagged
Molecular weight112.7 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized CD7 at 5 μg/ml can bind human SECTM1, the EC50 is 1.811-3.372 ng/ml.;Human CD7 protein hFc and Myc tag captured on COOH chip can bind Human SECTM1 protein hFc tag with an affinity constant of 1.84 nM as detected by LSPR Assay.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Biological Context

Subcellular Location: Apical cell membrane; Cell membrane (Single-pass type I membrane protein); Cell projection, cilium; Cytoplasm; Secreted

Product Specifications

Recombinant Macaca fascicularis Angiotensin-converting enzyme (ACE2), partial (Active) is a recombinant protein from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), expressed in Mammalian cell, covering amino acids 18-741aa, with C-terminal hFc1-tagged tag, molecular weight 112.7 kDa, purity Greater than 90% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized CD7 at 5 μg/ml can bind human SECTM1, the EC50 is 1.811-3.372 ng/ml.;Human CD7 protein hFc and Myc tag captured on COOH chip can bind Human SECTM1 protein hFc tag with an affinity constant of 1.84 nM as detected by LSPR Assay.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Subcellular Location

Apical cell membrane; Cell membrane (Single-pass type I membrane protein); Cell projection, cilium; Cytoplasm; Secreted

Subunit

Homodimer. Interacts with the catalytically active form of TMPRSS2. Interacts with SLC6A19; this interaction is essential for expression and function of SLC6A19 in intestine. Interacts with ITGA5:ITGB1. Probably interacts (via endocytic sorting signal motif) with AP2M1; the interaction is inhibited by phosphorylation of Tyr-781. Interacts (via PDZ-binding motif) with NHERF1 (via PDZ domains); the interaction may enhance ACE2 membrane residence

Organism: Macaca fascicularis

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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