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Recombinant Paguma larvata Angiotensin-converting enzyme 2 (ACE2), partial (Active)

Recombinant Paguma larvata Angiotensin-converting enzyme 2 (ACE2), partial (Active) — recombinant protein from Paguma larvata (Masked palm civet), expressed in Mammalian cell. Purity >90%.

SKU: BCACP-000094 Categories: ,
Product SKUBCACP-000094
Product DescriptionRecombinant Masked palm civet Angiotensin-converting enzyme 2 (ACE2) protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 18-740aa. [Accession | Q56NL1].
Uniprot No.Q56NL1
Gene NamesACE2
PurityGreater than 90% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region18-740aa
SpeciesPaguma larvata (Masked palm civet)
Tag InfoC-terminal hFc1-tagged
Molecular weight112.7 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized CD40 at 2 μg/ml can bind CD40L , the EC50 is 3.112-3.858 ng/ml.;Human CD40 protein hFc tag captured on COOH chip can bind Human CD40L protein hFc and Flag tag with an affinity constant of 2.06 nM as detected by LSPR Assay.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesACE-related carboxypeptidase

Function

(Microbial infection) Acts as a receptor for human coronavirus SARS.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein); Cytoplasm; Cell projection, cilium; Apical cell membrane

Product Specifications

Recombinant Paguma larvata Angiotensin-converting enzyme 2 (ACE2), partial (Active) is a recombinant protein from Paguma larvata (Masked palm civet), expressed in Mammalian cell, covering amino acids 18-740aa, with C-terminal hFc1-tagged tag, molecular weight 112.7 kDa, purity Greater than 90% as determined by SDS-PAGE.Greater than 90% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

(Microbial infection) Acts as a receptor for human coronavirus SARS

Subcellular Location

Cell membrane (Single-pass type I membrane protein); Cytoplasm; Cell projection, cilium; Apical cell membrane

Subunit

(Microbial infection) Interacts with SARS-CoV S protein

Gene: ACE2  |  Organism: Paguma larvata  |  Synonyms: ACE-related carboxypeptidase

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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