Recombinant Macaca fascicularis Glucagon-like peptide 1 receptor (GLP1R), partial (Active), Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), Mammalian cell, C-terminal 10xHis-tagged, 15.5 kDa, purity >90% as determined by SDS-PAGE.

Recombinant Macaca fascicularis Glucagon-like peptide 1 receptor (GLP1R), partial (Active)

Recombinant Macaca fascicularis Glucagon-like peptide 1 receptor (GLP1R), partial (Active) — G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Purity >90%.

SKU: BCACP-000317 Category:
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Product SKUBCACP-000317
Product DescriptionRecombinant Cynomolgus monkey Glucagon-like peptide 1 receptor (GLP1R) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 24-144aa. [Accession | F8V479].
Uniprot No.F8V479
Gene NamesGLP1R
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region24-144aa
SpeciesMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Tag InfoC-terminal 10xHis-tagged
Molecular weight15.5 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Anti-CLEC9A recombinant antibody at 2 μg/mL can bind Human CLEC9A protein. The EC50 is 2.915-3.520 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesGlucagon-like peptide 1 receptor; GLP1R

Function

G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)

Product Specifications

Recombinant Macaca fascicularis Glucagon-like peptide 1 receptor (GLP1R), partial (Active) is a recombinant protein from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), expressed in Mammalian cell, covering amino acids 24-144aa, with C-terminal 10xHis-tagged tag, molecular weight 15.5 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Anti-CLEC9A recombinant antibody at 2 μg/mL can bind Human CLEC9A protein. The EC50 is 2.915-3.520 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Subunit

May form homodimers and heterodimers with GIPR

Gene: GLP1R  |  Organism: Macaca fascicularis

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

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Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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