Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), patial (Active), Rattus norvegicus (Rat), Mammalian cell, C-terminal 10xHis-tagged, 14.9 kDa, purity >90% as determined by SDS-PAGE.

Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), patial (Active)

Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), patial (Active) — G protein-coupled receptor for glucagon-like peptide 1 (GLP-1). Purity >90%.

SKU: BCACP-000362 Category:
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Product SKUBCACP-000362
Product DescriptionRecombinant Rat Glucagon-like peptide 1 receptor (Glp1r), patial protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 22-139aa. [Accession | P32301].
Uniprot No.P32301
Gene NamesGlp1r
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region22-139aa
SpeciesRattus norvegicus (Rat)
Tag InfoC-terminal 10xHis-tagged
Molecular weight14.9 kDa
ActivityThe ED50 as determined by the dose-dependent stimulation of the proliferation of TF-1 cells is 0.4476-1.272 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesGlucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R; Glp1r; Glpr

Function

G protein-coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)
Tissue Specificity: Pancreatic islets, stomach, lung, rat insulinoma cell line

Product Specifications

Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), patial (Active) is a recombinant protein from Rattus norvegicus (Rat), expressed in Mammalian cell, covering amino acids 22-139aa, with C-terminal 10xHis-tagged tag, molecular weight 14.9 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of TF-1 cells is 0.4476-1.272 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

G protein-coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:1326760, PubMed:7527026, PubMed:7813606). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (PubMed:1326760, PubMed:7813606). Plays a role in regulating insulin secretion in response to GLP-1 (By similarity)

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Tissue Specificity

Pancreatic islets, stomach, lung, rat insulinoma cell line

Subunit

May form homodimers and heterodimers with GIPR

Gene: Glp1r  |  Organism: Rattus norvegicus

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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