Recombinant Macaca fascicularis Neural cell adhesion molecule L1 (L1CAM), partial (Active)

Recombinant Macaca fascicularis Neural cell adhesion molecule L1 (L1CAM), partial (Active) — Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. Purity >95%.

SKU: BCACP-000473 Category:
Product SKUBCACP-000473
Product DescriptionRecombinant Cynomolgus monkey Neural cell adhesion molecule L1 (L1CAM) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 20-1120aa. [Accession | A0A2K5URB5].
Uniprot No.A0A2K5URB5
Gene NamesL1CAM
PurityGreater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region20-1120aa
SpeciesMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Tag InfoC-terminal 10xHis-tagged
Molecular weight124.5 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Macaca fascicularis CRLF2 at 2 μg/mL can bind Anti-CRLF2 recombinant antibody. The EC50 is 2.079-2.450 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesNeural cell adhesion molecule L1; L1CAM

Function

Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.

Product Specifications

Recombinant Macaca fascicularis Neural cell adhesion molecule L1 (L1CAM), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 20-1120aa, with C-terminal 10xHis-tagged tag, molecular weight 124.5 kDa, purity Greater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Macaca fascicularis CRLF2 at 2 μg/mL can bind Anti-CRLF2 recombinant antibody. The EC50 is 2.079-2.450 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity

Organism: Macaca fascicularis

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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