Recombinant Mouse Activin receptor type-2A (Acvr2a), partial (Active), Mus musculus (Mouse), Mammalian cell, C-terminal 10xHis-tagged, 14.8 kDa, purity >95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.

Recombinant Mouse Activin receptor type-2A (Acvr2a), partial (Active)

Recombinant Mouse Activin receptor type-2A (Acvr2a), partial (Active) — On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Purity >95%.

SKU: BCACP-000337 Category:
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Product SKUBCACP-000337
Product DescriptionRecombinant Mouse Activin receptor type-2A (Acvr2a) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 20-135aa. [Accession | P27038].
Uniprot No.P27038
Gene NamesACVR2A
PurityGreater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region20-135aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 10xHis-tagged
Molecular weight14.8 kDa
ActivityMeasured by its ability to hydrolyze p-nitrophenylacetate. The specific activity is >40000 pmol/min/µg.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesActivin receptor type-2A; EC:2.7.11.30; Activin receptor type IIA (ACTR-IIA); Acvr2a; Acvr2

Function

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

Product Specifications

Recombinant Mouse Activin receptor type-2A (Acvr2a), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 20-135aa, with C-terminal 10xHis-tagged tag, molecular weight 14.8 kDa, purity Greater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its ability to hydrolyze p-nitrophenylacetate. The specific activity is >40000 pmol/min/µg.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6 (PubMed:23527555)

Gene: Acvr2a  |  Organism: Mus musculus

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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