Recombinant Mouse BDNF/NT-3 growth factors receptor Protein, Insect cell, N-6His, 45.7kDa (409aa) 57-70KDa (SDS-PAGE under reducing conditions.), purity >90% as determined by SDS-PAGE.
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Recombinant Mouse BDNF/NT-3 growth factors receptor Protein

Recombinant Mouse BDNF/NT-3 growth factors receptor Protein — Important signaling molecule that activates signaling cascades downstream of NTRK2. Purity >90%.

SKU: BCRETP-000025 Categories: ,
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Product Specifications

Product SkuBCRETP-000025
Product DescriptionRecombinant Mouse BDNF/NT-3 growth factors receptor Protein is expressed from Insect Cells with His tag at the N-Terminus. It contains 32-429aa. [Accession | P21237].
Uniprot No.P21237
SynonymsNtrk2, GP145-TrkB/GP95-TrkB, Tkrb, trk-B, trkB
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemInsect cell
Expression Region32-429aa
Tag InfoN-6His
Molecular weight45.7kDa (409aa) 57-70KDa (SDS-PAGE under reducing conditions.)
EndotoxinLess than 1.0 EU/μg as determined by LAL method.

Function

Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD).

Product Specifications

Recombinant Mouse BDNF/NT-3 growth factors receptor Protein is a recombinant protein, expressed in Insect cell, covering amino acids 32-429aa, with N-6His tag, molecular weight 45.7kDa (409aa) 57-70KDa (SDS-PAGE under reducing conditions.), purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Important signaling molecule that activates signaling cascades downstream of NTRK2 (PubMed:27457814). Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2 (PubMed:24908487, PubMed:29909994). Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD) (PubMed:27457814). Binding to NGFR and SORCS2 promotes neuronal apoptosis (PubMed:24908487). Promotes neuronal growth cone collapse (PubMed:24908487, PubMed:27457814)

Gene: Bdnf  |  Organism: Mus musculus

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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