Recombinant Mouse C-C motif chemokine 12 protein (Ccl12), Mus musculus (Mouse), E.Coli, Tag-Free, 9.3 kDa, purity >>95% as determined by SDS-PAGE.
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Recombinant Mouse C-C motif chemokine 12 protein (Ccl12)

Recombinant Mouse C-C motif chemokine 12 protein (Ccl12) — Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Purity >95%.

SKU: BCACP-000805 Categories: ,
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Product SKUBCACP-000805
Product DescriptionRecombinant Mouse C-C motif chemokine 12 protein (Ccl12) protein is expressed from E.Coli with Tag-Free. It contains 23-104aa. [Accession | Q62401].
Uniprot No.Q62401
Gene NamesCcl12
Purity>95% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region23-104aa
SpeciesMus musculus (Mouse)
Tag InfoTag-Free
Molecular weight9.3 kDa
ActivityFully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine T-lymphocytes is in a concentration range of 10-100 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesC-C motif chemokine 12; Ccl12; CCL12_MOUSE; Macrophage/monocyte Chemotactic Protein; MCP-1-related chemokine; MCP-5; Monocyte chemoattractant protein 5; Monocyte chemotactic protein 5; OTTMUSP00000000792; Scya12; Small inducible cytokine A12; Small-inducible cytokine A12

Function

Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Predominantly expressed in the lymph nodes and thymus. Also found in the salivary glands containing lymph nodes, breast, heart, lung, brain, small intestine, kidney and colon

Product Specifications

Recombinant Mouse C-C motif chemokine 12 protein (Ccl12) is a recombinant protein from Mus musculus (Mouse), expressed in E.Coli, covering amino acids 23-104aa, with Tag-Free tag, molecular weight 9.3 kDa, purity >95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine T-lymphocytes is in a concentration range of 10-100 ng/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation

Subcellular Location

Secreted

Tissue Specificity

Predominantly expressed in the lymph nodes and thymus. Also found in the salivary glands containing lymph nodes, breast, heart, lung, brain, small intestine, kidney and colon

Subunit

Homodimer

Gene: Ccl12  |  Organism: Mus musculus  |  Synonyms: MCP-1-related chemokine; Monocyte chemoattractant protein 5; Monocyte chemotactic protein 5; Small-inducible cytokine A12

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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