Recombinant Mouse C-C motif chemokine 19 protein (Ccl19), Mus musculus (Mouse), E.Coli, Tag-Free, 9.2 kDa, purity >>97% as determined by SDS-PAGE.
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Recombinant Mouse C-C motif chemokine 19 protein (Ccl19)

Recombinant Mouse C-C motif chemokine 19 protein (Ccl19) — Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. Purity >97%.

SKU: BCACP-000806 Categories: ,
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Product SKUBCACP-000806
Product DescriptionRecombinant Mouse C-C motif chemokine 19 protein (Ccl19) protein is expressed from E.Coli with Tag-Free. It contains 26-108aa. [Accession | O70460].
Uniprot No.O70460
Gene NamesCcl19
Purity>97% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region26-108aa
SpeciesMus musculus (Mouse)
Tag InfoTag-Free
Molecular weight9.2 kDa
ActivityNot Test
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesCcl19; Elc; Scya19; C-C motif chemokine 19; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Small-inducible cytokine A19

Function

Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Highly expressed by dendritic cells in mesenteric and peripheral lymph nodes. Significant expression in spleen (T cell zone or periarteriolar lymphatic sheath) and Peyer patches. Low expression in thymus

Product Specifications

Recombinant Mouse C-C motif chemokine 19 protein (Ccl19) is a recombinant protein from Mus musculus (Mouse), expressed in E.Coli, covering amino acids 26-108aa, with Tag-Free tag, molecular weight 9.2 kDa, purity >97% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not Test

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4

Subcellular Location

Secreted

Tissue Specificity

Highly expressed by dendritic cells in mesenteric and peripheral lymph nodes. Significant expression in spleen (T cell zone or periarteriolar lymphatic sheath) and Peyer patches. Low expression in thymus

Subunit

Interacts with TNFAIP6 (via Link domain)

Gene: Ccl19  |  Organism: Mus musculus  |  Synonyms: Epstein-Barr virus-induced molecule 1 ligand chemokine; Small-inducible cytokine A19

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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