Recombinant Mouse C-C motif chemokine 21c (Ccl21c), Mus musculus (Mouse), E.coli, Tag-Free, 12.8kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Mouse C-C motif chemokine 21c (Ccl21c)

Recombinant Mouse C-C motif chemokine 21c (Ccl21c) — Binds to chemokine receptors CCR7 and CXCR3. Purity >85%.

SKU: BCRECP-002306 Categories: ,
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Product Specifications

Product SkuBCRECP-002306
Product DescriptionRecombinant Mouse C-C motif chemokine 21c (Ccl21c) Protein is expressed from E.coli with Tag-Free. It contains 24-133aa. [Accession | P86793].
Uniprot No.P86793
Gene NamesCcl21c
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region24-133aa
SpeciesMus musculus (Mouse)
Tag InfoTag-Free
Molecular weight12.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Binds to chemokine receptors CCR7 and CXCR3. Also binds to G protein-coupled receptor GPR174. Inhibits hemopoiesis and stimulates chemotaxis.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed strongly in lung, spleen, thymus, peripheral and mesentric lymph nodes. Also expressed in the testis, kidney, liver, and heart

Product Specifications

Recombinant Mouse C-C motif chemokine 21c (Ccl21c) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 24-133aa, with Tag-Free tag, molecular weight 12.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Binds to chemokine receptors CCR7 and CXCR3. Also binds to G protein-coupled receptor GPR174 (By similarity). Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs

Subcellular Location

Secreted

Tissue Specificity

Expressed strongly in lung, spleen, thymus, peripheral and mesentric lymph nodes. Also expressed in the testis, kidney, liver, and heart

Subunit

Monomer (By similarity). Interacts with PDPN; relocalizes PDPN to the basolateral membrane (By similarity). Interacts with TNFAIP6 (via Link domain) (By similarity)

Gene: Ccl21c  |  Organism: Mus musculus  |  Synonyms: 6Ckine; Beta-chemokine exodus-2; Small-inducible cytokine A21c; Thymus-derived chemotactic agent 4

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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