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Recombinant Mouse C-C motif chemokine 27 protein (Ccl27) (Active)

Recombinant Mouse C-C motif chemokine 27 protein (Ccl27) (Active) — Chemotactic factor that attracts skin-associated memory T-lymphocytes. Purity >98%.

SKU: BCACP-000812 Categories: ,
Product SKUBCACP-000812
Product DescriptionRecombinant Mouse C-C motif chemokine 27 protein (Ccl27) protein is expressed from E.Coli with Tag-Free. It contains 26-120aa. [Accession | Q9Z1X0].
Uniprot No.Q9Z1X0
Gene NamesCcl27
Purity>98% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region26-120aa
SpeciesMus musculus (Mouse)
Tag InfoTag-Free
Molecular weight10.9 kDa
ActivityFully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 5-50 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesCcl27; Ilc; Scya27C-C motif chemokine 27; CC chemokine ILC; Cutaneous T-cell-attracting chemokine; CTACK; ESkine; IL-11 R-alpha-locus chemokine; ALP; mILC; Skinkine; Small-inducible cytokine A27

Function

Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis.

Biological Context

Subcellular Location: Nucleus
Tissue Specificity: Isoform 1 is predominantly expressed in placenta and weakly in skin. Isoform 2 is predominantly expressed in testes and brain, weakly in kidney and liver and even lower in heart and muscle. Low expression of both isoforms in other tissues

Product Specifications

Recombinant Mouse C-C motif chemokine 27 protein (Ccl27) (Active) is a recombinant protein from Mus musculus (Mouse), expressed in E.Coli, covering amino acids 26-120aa, with Tag-Free tag, molecular weight 10.9 kDa, purity >98% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 5-50 ng/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10

Subcellular Location

Nucleus

Tissue Specificity

Isoform 1 is predominantly expressed in placenta and weakly in skin. Isoform 2 is predominantly expressed in testes and brain, weakly in kidney and liver and even lower in heart and muscle. Low expression of both isoforms in other tissues

Subunit

Monomer, dimer, and tetramer. Heparin avidly promotes oligomerization. Interacts with TNFAIP6 (via Link domain)

Gene: Ccl27  |  Organism: Mus musculus  |  Synonyms: CC chemokine ILC; Cutaneous T-cell-attracting chemokine; ESkine; IL-11 R-alpha-locus chemokine; Skinkine; Small-inducible cytokine A27
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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