Recombinant Mouse Calcitonin gene-related peptide 1 (Calca), partial, Mus musculus (Mouse), Mammalian cell, N-terminal hFc-tagged, 29.9kDa, purity >95% as determined by SDS-PAGE.

Recombinant Mouse Calcitonin gene-related peptide 1 (Calca), partial

Recombinant Mouse Calcitonin gene-related peptide 1 (Calca), partial — CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Purity >95%.

SKU: BCRECP-002287 Category:
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Product Specifications

Product SkuBCRECP-002287
Product DescriptionRecombinant Mouse Calcitonin gene-related peptide 1 (Calca) Protein is expressed from Mammalian cell with N-terminal hFc-tagged. It contains 83-119aa. [Accession | Q99JA0].
Uniprot No.Q99JA0
Gene NamesCalca
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region83-119aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal hFc-tagged
Molecular weight29.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Detected in nerve cells of cerebrum, hippocampus and pons/midbrain in newborns, and only in nerve cells of pons/midbrain in adult

Product Specifications

Recombinant Mouse Calcitonin gene-related peptide 1 (Calca), partial is a recombinant protein from Mus musculus (Mouse), expressed in Mammalian cell, covering amino acids 83-119aa, with N-terminal hFc-tagged tag, molecular weight 29.9kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex

Subcellular Location

Secreted

Tissue Specificity

Detected in nerve cells of cerebrum, hippocampus and pons/midbrain in newborns, and only in nerve cells of pons/midbrain in adult

Gene: Calca  |  Organism: Mus musculus  |  Synonyms: Alpha-type CGRP; Calcitonin gene-related peptide I

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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