Recombinant Mouse Chordin-like protein 1 (Chrdl1), Mus musculus (Mouse), Baculovirus, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 52.2kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse Chordin-like protein 1 (Chrdl1)

Recombinant Mouse Chordin-like protein 1 (Chrdl1) — Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Purity >85%.

SKU: BCRECP-002369 Category:
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Product Specifications

Product SkuBCRECP-002369
Product DescriptionRecombinant Mouse Chordin-like protein 1 (Chrdl1) Protein is expressed from Baculovirus with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 23-447aa. [Accession | Q920C1].
Uniprot No.Q920C1
Gene NamesChrdl1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemBaculovirus
Expression Region23-447aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight52.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed in heart, brain, lung, liver, kidney and testis

Product Specifications

Recombinant Mouse Chordin-like protein 1 (Chrdl1) is a recombinant protein from Mus musculus (Mouse), expressed in Baculovirus, covering amino acids 23-447aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 52.2kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation (By similarity). Antagonizes the function of BMP7 and may thus play an important role in the embryonic bone formation. Shows no inhibitory effect on the inducing activity of BMP2. Plays a role during anterior segment eye development (By similarity)

Subcellular Location

Secreted

Tissue Specificity

Expressed in heart, brain, lung, liver, kidney and testis

Gene: Chrdl1  |  Organism: Mus musculus  |  Synonyms: Neuralin-1; Neurogenesin-1; Ventroptin

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

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Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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