Recombinant Mouse G-protein coupled receptor 171 (Gpr171) Protein, Mus musculus (Mouse), in vitro E.coli expression system, N-terminal 10xHis-tagged, 42.8kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse G-protein coupled receptor 171 (Gpr171) Protein

Recombinant Mouse G-protein coupled receptor 171 (Gpr171) Protein — G protein-coupled receptor for Big LEN, a 16-amino acid neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N). Purity >85%.

SKU: BCRECP-00190TM Category:
Online Inquiry →

Product Specifications

Uniprot No.Q8BG55
Gene NamesGpr171
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region1-319aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged
Molecular weight42.8kDa
ActivityNot Test
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

G protein-coupled receptor for Big LEN, a 16-amino acid neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N). Acts through a G(i)-alpha-mediated pathway in response to Big LEN. Big LEN-GPR171 system plays an important role in regulating feeding and metabolism.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)
Tissue Specificity: Highly expressed in hypothalamus, including the arcuate nucleus, paraventricular nucleus and dorsomedial hypothalamus. Expressed in periaqueductal gray (at protein level), found primarily in GABAergic neurons and to a lesser extent in glutamatergic neurons. Expressed in T cells and natural killer cells

Product Specifications

Recombinant Mouse G-protein coupled receptor 171 (Gpr171) Protein is a recombinant protein from Mus musculus (Mouse), expressed in in vitro E.coli expression system, covering amino acids 1-319aa, with N-terminal 10xHis-tagged tag, molecular weight 42.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not Test

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

G protein-coupled receptor for Big LEN, a 16-amino acid neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N) (PubMed:24043826, PubMed:28425495). Acts through a G(i)-alpha-mediated pathway in response to Big LEN (PubMed:24043826). Big LEN-GPR171 system plays an important role in regulating feeding and metabolism (PubMed:24043826). Also plays a role in modulating fear and anxiety-like behaviors in the basolateral amygdala (PubMed:28425495). Big LEN-GPR171 modulates the mu-type opioid receptor signaling and antinociception (PubMed:31308196). Acts as a negative regulator T cell function (PubMed:34615877)

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Tissue Specificity

Highly expressed in hypothalamus, including the arcuate nucleus, paraventricular nucleus and dorsomedial hypothalamus (PubMed:24043826). Expressed in periaqueductal gray (at protein level), found primarily in GABAergic neurons and to a lesser extent in glutamatergic neurons (PubMed:31308196). Expressed in T cells and natural killer cells (PubMed:34615877)

Gene: Gpr171  |  Organism: Mus musculus
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top