Recombinant Mouse Heat shock protein 75 kDa, mitochondrial (Trap1)

Recombinant Mouse Heat shock protein 75 kDa, mitochondrial (Trap1) — Chaperone that expresses an ATPase activity. Purity >85%.

SKU: BCRECP-004612 Category:

Product Specifications

Product SkuBCRECP-004612
Product DescriptionRecombinant Mouse Heat shock protein 75 kDa, mitochondrial (Trap1) Protein is expressed from Yeast with C-terminal 6xHis-tagged. It contains 61-706aa. [Accession | Q9CQN1].
Uniprot No.Q9CQN1
Gene NamesTrap1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region61-706aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 6xHis-tagged
Molecular weight74.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis.

Biological Context

Subcellular Location: Mitochondrion; Mitochondrion inner membrane; Mitochondrion matrix

Product Specifications

Recombinant Mouse Heat shock protein 75 kDa, mitochondrial (Trap1) is a recombinant protein from Mus musculus (Mouse), expressed in Yeast, covering amino acids 61-706aa, with C-terminal 6xHis-tagged tag, molecular weight 74.7kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA

Subcellular Location

Mitochondrion; Mitochondrion inner membrane; Mitochondrion matrix

Subunit

Binds to the intracellular domain of tumor necrosis factor type 1 receptor. Binds to RB1. Interacts with SRC. Interacts with SDHA

Gene: Trap1  |  Organism: Mus musculus  |  Synonyms: TNFR-associated protein 1; Tumor necrosis factor type 1 receptor-associated protein

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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