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Recombinant Mouse Insulin-like growth factor-binding protein 7 (Igfbp7)

Recombinant Mouse Insulin-like growth factor-binding protein 7 (Igfbp7) — Binds IGF1 and IGF2 with a relatively low affinity. Purity >90%.

SKU: BCRECP-003094 Categories: ,

Product Specifications

Product SkuBCRECP-003094
Product DescriptionRecombinant Mouse Insulin-like growth factor-binding protein 7 (Igfbp7) Protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 26-281aa. [Accession | Q61581].
Uniprot No.Q61581
Gene NamesIgfbp7
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region26-281aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal hFc1-tagged
Molecular weight55.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed at high levels in lung, kidney, small intestine, testis and uterus and at moderate levels in liver

Product Specifications

Recombinant Mouse Insulin-like growth factor-binding protein 7 (Igfbp7) is a recombinant protein from Mus musculus (Mouse), expressed in Mammalian cell, covering amino acids 26-281aa, with C-terminal hFc1-tagged tag, molecular weight 55.3kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Acts as a ligand for CD93 to play a role in angiogenesis

Subcellular Location

Secreted

Tissue Specificity

Expressed at high levels in lung, kidney, small intestine, testis and uterus and at moderate levels in liver

Subunit

May interact with VPS24/CHMP3; the relevance of such interaction however remains unclear. Interacts with CD93; this interaction plays a role in endothelial cells angiogenesis

Gene: Igfbp7  |  Organism: Mus musculus  |  Synonyms: MAC25 protein
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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